Wird geladen...
A slow conformational switch in the BMAL1 transactivation domain modulates circadian rhythms
The C-terminal transactivation domain (TAD) of BMAL1 (Brain and muscle ARNT-like 1) is a regulatory hub for transcriptional coactivators and repressors that compete for binding and consequently contributes to period determination of the mammalian circadian clock. Here, we report the discovery of two...
Gespeichert in:
| Veröffentlicht in: | Mol Cell |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484534/ https://ncbi.nlm.nih.gov/pubmed/28506462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.04.011 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|