A slow conformational switch in the BMAL1 transactivation domain modulates circadian rhythms

The C-terminal transactivation domain (TAD) of BMAL1 (Brain and muscle ARNT-like 1) is a regulatory hub for transcriptional coactivators and repressors that compete for binding and consequently contributes to period determination of the mammalian circadian clock. Here, we report the discovery of two...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Gustafson, Chelsea L., Parsley, Nicole C., Asimgil, Hande, Lee, Hsiau-Wei, Ahlbach, Christopher, Michael, Alicia K., Xu, Haiyan, Williams, Owen L., Davis, Tara L., Liu, Andrew C., Partch, Carrie L.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484534/
https://ncbi.nlm.nih.gov/pubmed/28506462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.04.011
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires