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Emerging Models for the Molecular Basis of Mammalian Circadian Timing
[Image: see text] Mammalian circadian timekeeping arises from a transcription-based feedback loop driven by a set of dedicated clock proteins. At its core, the heterodimeric transcription factor CLOCK:BMAL1 activates expression of Period, Cryptochrome, and Rev-Erb genes, which feed back to repress t...
Gespeichert in:
| Veröffentlicht in: | Biochemistry |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American
Chemical Society
2014
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303291/ https://ncbi.nlm.nih.gov/pubmed/25303119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500731f |
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