The human CRY1 tail controls circadian timing by regulating its association with CLOCK:BMAL1

Circadian rhythms are generated by interlocked transcription–translation feedback loops that establish cell-autonomous biological timing of ∼24 h. Mutations in core clock genes that alter their stability or affinity for one another lead to changes in circadian period. The human CRY1Δ11 mutant length...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Parico, Gian Carlo G., Perez, Ivette, Fribourgh, Jennifer L., Hernandez, Britney N., Lee, Hsiau-Wei, Partch, Carrie L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2020
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668087/
https://ncbi.nlm.nih.gov/pubmed/33106415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920653117
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