Loss of prion protein induces a primed state of type I interferon-responsive genes

The cellular prion protein (PrP(C)) has been extensively studied because of its pivotal role in prion diseases; however, its functions remain incompletely understood. A unique line of goats has been identified that carries a nonsense mutation that abolishes synthesis of PrP(C). In these animals, the...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Malachin, Giulia, Reiten, Malin R., Salvesen, Øyvind, Aanes, Håvard, Kamstra, Jorke H., Skovgaard, Kerstin, Heegaard, Peter M. H., Ersdal, Cecilie, Espenes, Arild, Tranulis, Michael A., Bakkebø, Maren K.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484497/
https://ncbi.nlm.nih.gov/pubmed/28651013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179881
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items