Recombinant Modified Vaccinia Virus Ankara Expressing the Spike Glycoprotein of Severe Acute Respiratory Syndrome Coronavirus Induces Protective Neutralizing Antibodies Primarily Targeting the Receptor Binding Region

Immunization with a killed or inactivated viral vaccine provides significant protection in animals against challenge with certain corresponding pathogenic coronaviruses (CoVs). However, the promise of this approach in humans is hampered by serious concerns over the risk of leaking live severe acute...

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Dades bibliogràfiques
Autors principals: Chen, Zhiwei, Zhang, Linqi, Qin, Chuan, Ba, Lei, Yi, Christopher E., Zhang, Fengwen, Wei, Qiang, He, Tian, Yu, Wenjie, Yu, Jian, Gao, Hong, Tu, Xinming, Gettie, Agegnehu, Farzan, Michael, Yuen, Kwok-yung, Ho, David D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC548443/
https://ncbi.nlm.nih.gov/pubmed/15708987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.2678-2688.2005
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