Single Amino Acid Substitutions in the Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Determine Viral Entry and Immunogenicity of a Major Neutralizing Domain

Neutralizing antibodies (NAbs) against severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) spike (S) glycoprotein confer protection to animals experimentally infected with the pathogenic virus. We and others previously demonstrated that a major mechanism for neutralizing SARS-CoV was thr...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Yi, Christopher E., Ba, Lei, Zhang, Linqi, Ho, David D., Chen, Zhiwei
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2005
נושאים:
Pathogenesis and Immunity
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1212612/
https://ncbi.nlm.nih.gov/pubmed/16140741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.18.11638-11646.2005
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