Natural Mutations in the Receptor Binding Domain of Spike Glycoprotein Determine the Reactivity of Cross-Neutralization between Palm Civet Coronavirus and Severe Acute Respiratory Syndrome Coronavirus

The severe acute respiratory syndrome (SARS) outbreak of 2002 and 2003 occurred as a result of zoonotic transmission. Coronavirus (CoV) found in naturally infected palm civet (civet-CoV) represents the closest genetic relative to SARS-CoV, but the degree and the determinants of cross-neutralization...

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Detalhes bibliográficos
Main Authors: Liu, Li, Fang, Qing, Deng, Fei, Wang, Hanzhong, Yi, Christopher E., Ba, Lei, Yu, Wenjie, Lin, Richard D., Li, Taisheng, Hu, Zhihong, Ho, David D., Zhang, Linqi, Chen, Zhiwei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900161/
https://ncbi.nlm.nih.gov/pubmed/17314167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02389-06
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