Middle East Respiratory Syndrome Coronavirus Spike Protein Delivered by Modified Vaccinia Virus Ankara Efficiently Induces Virus-Neutralizing Antibodies

Middle East respiratory syndrome coronavirus (MERS-CoV) has recently emerged as a causative agent of severe respiratory disease in humans. Here, we constructed recombinant modified vaccinia virus Ankara (MVA) expressing full-length MERS-CoV spike (S) protein (MVA-MERS-S). The genetic stability and g...

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Hlavní autoři: Song, Fei, Fux, Robert, Provacia, Lisette B., Volz, Asisa, Eickmann, Markus, Becker, Stephan, Osterhaus, Albert D. M. E., Haagmans, Bart L., Sutter, Gerd
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807317/
https://ncbi.nlm.nih.gov/pubmed/23986586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01672-13
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