Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer’s and Other Neurodegenerative Diseases

[Image: see text] Alzheimer’s disease (AD) is a complex, multifactorial disease in which different neuropathological mechanisms are likely involved, including those associated with pathological tau and Aβ species as well as neuroinflammation. In this context, the development of single multitargeted...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Cornec, Anne-Sophie, Monti, Ludovica, Kovalevich, Jane, Makani, Vishruti, James, Michael J., Vijayendran, Krishna G., Oukoloff, Killian, Yao, Yuemang, Lee, Virginia M.-Y., Trojanowski, John Q., Smith, Amos B., Brunden, Kurt R., Ballatore, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483893/
https://ncbi.nlm.nih.gov/pubmed/28530811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.7b00475
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