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Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer’s and Other Neurodegenerative Diseases

[Image: see text] Alzheimer’s disease (AD) is a complex, multifactorial disease in which different neuropathological mechanisms are likely involved, including those associated with pathological tau and Aβ species as well as neuroinflammation. In this context, the development of single multitargeted...

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Vydáno v:J Med Chem
Hlavní autoři: Cornec, Anne-Sophie, Monti, Ludovica, Kovalevich, Jane, Makani, Vishruti, James, Michael J., Vijayendran, Krishna G., Oukoloff, Killian, Yao, Yuemang, Lee, Virginia M.-Y., Trojanowski, John Q., Smith, Amos B., Brunden, Kurt R., Ballatore, Carlo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2017
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483893/
https://ncbi.nlm.nih.gov/pubmed/28530811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.7b00475
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