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Limited TTP supply affects telomere length regulation in a telomerase-independent fashion
An adequate supply of nucleotides is essential for DNA replication and DNA repair. Moreover, inhibition of TTP synthesis can cause cell death by a poorly characterized mechanism called thymine-less death. In the yeast Saccharomyces cerevisiae, the genes encoding thymidylate synthetase (CDC21) and th...
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| Gepubliceerd in: | Nucleic Acids Res |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2005
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548361/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15681620/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gki219 |
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