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Limited TTP supply affects telomere length regulation in a telomerase-independent fashion
An adequate supply of nucleotides is essential for DNA replication and DNA repair. Moreover, inhibition of TTP synthesis can cause cell death by a poorly characterized mechanism called thymine-less death. In the yeast Saccharomyces cerevisiae, the genes encoding thymidylate synthetase (CDC21) and th...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2005
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548361/ https://ncbi.nlm.nih.gov/pubmed/15681620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki219 |
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