Enhancing the Oncolytic Activity of CD133-Targeted Measles Virus: Receptor Extension or Chimerism with Vesicular Stomatitis Virus Are Most Effective

Therapy resistance and tumor recurrence are often linked to a small refractory and highly tumorigenic subpopulation of neoplastic cells, known as cancer stem cells (CSCs). A putative marker of CSCs is CD133 (prominin-1). We have previously described a CD133-targeted oncolytic measles virus (MV-CD133...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Kleinlützum, Dina, Hanauer, Julia D. S., Muik, Alexander, Hanschmann, Kay-Martin, Kays, Sarah-Katharina, Ayala-Breton, Camilo, Peng, Kah-Whye, Mühlebach, Michael D., Abel, Tobias, Buchholz, Christian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483446/
https://ncbi.nlm.nih.gov/pubmed/28695108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2017.00127
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