Oncolytic Virus with Attributes of Vesicular Stomatitis Virus and Measles Virus in Hepatobiliary and Pancreatic Cancers

Recombinant vesicular stomatitis virus (VSV)-fusion and hemagglutinin (FH) was developed by substituting the promiscuous VSV-G glycoprotein (G) gene in the backbone of VSV with genes encoding for the measles virus envelope proteins F and H. Hybrid VSV-FH exhibited a multifaceted mechanism of cancer-...

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Veröffentlicht in:Mol Ther Oncolytics
Hauptverfasser: Nagalo, Bolni Marius, Breton, Camilo Ayala, Zhou, Yumei, Arora, Mansi, Bogenberger, James M., Barro, Oumar, Steele, Michael B., Jenks, Nathan J., Baker, Alexander T., Duda, Dan G., Roberts, Lewis Rowland, Russell, Stephen J., Peng, Kah Whye, Borad, Mitesh J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7437509/
https://ncbi.nlm.nih.gov/pubmed/32839735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.08.007
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