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Characteristics of Oncolytic Vesicular Stomatitis Virus Displaying Tumor-Targeting Ligands

We sought proof of principle that tumor-targeting ligands can be displayed on the surface of vesicular stomatitis virus (VSV) by engineering its glycoprotein. Here, we successfully rescued VSVs displaying tumor vasculature-targeting ligands. By using a rational approach, we investigated various feas...

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Bibliografske podrobnosti
Main Authors: Ammayappan, Arun, Peng, Kah-Whye, Russell, Stephen J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838279/
https://ncbi.nlm.nih.gov/pubmed/24089573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02240-13
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