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Neuroattenuation of Vesicular Stomatitis Virus through Picornaviral Internal Ribosome Entry Sites

Vesicular stomatitis virus (VSV) is potent and a highly promising agent for the treatment of cancer. However, translation of VSV oncolytic virotherapy into the clinic is being hindered by its inherent neurotoxicity. It has been demonstrated that selected picornaviral internal ribosome entry site (IR...

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Hlavní autoři: Ammayappan, Arun, Nace, Rebecca, Peng, Kah-Whye, Russell, Stephen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592162/
https://ncbi.nlm.nih.gov/pubmed/23283963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02984-12
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