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Highly Attenuated Recombinant Vesicular Stomatitis Virus VSV-12′GFP Displays Immunogenic and Oncolytic Activity

Vesicular stomatitis virus (VSV) has shown considerable promise both as an immunization vector and as an oncolytic virus. In both applications, an important concern is the safety profile of the virus. To generate a highly attenuated virus, we added two reporter genes to the 3′ end of the VSV genome,...

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Detalhes bibliográficos
Main Authors: van den Pol, Anthony N., Davis, John N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554062/
https://ncbi.nlm.nih.gov/pubmed/23135719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01106-12
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