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Highly Attenuated Recombinant Vesicular Stomatitis Virus VSV-12′GFP Displays Immunogenic and Oncolytic Activity

Vesicular stomatitis virus (VSV) has shown considerable promise both as an immunization vector and as an oncolytic virus. In both applications, an important concern is the safety profile of the virus. To generate a highly attenuated virus, we added two reporter genes to the 3′ end of the VSV genome,...

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Main Authors: van den Pol, Anthony N., Davis, John N.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554062/
https://ncbi.nlm.nih.gov/pubmed/23135719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01106-12
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