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Faster Replication and Higher Expression Levels of Viral Glycoproteins Give the Vesicular Stomatitis Virus/Measles Virus Hybrid VSV-FH a Growth Advantage over Measles Virus

VSV-FH is a hybrid vesicular stomatitis virus (VSV) with a deletion of its G glycoprotein and encoding the measles virus (MV) fusion (F) and hemagglutinin (H) envelope glycoproteins. VSV-FH infects cells expressing MV receptors and is fusogenic and effective against myeloma xenografts in mice. We ev...

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Detalhes bibliográficos
Main Authors: Ayala-Breton, Camilo, Russell, Luke O. J., Russell, Stephen J., Peng, Kah-Whye
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135973/
https://ncbi.nlm.nih.gov/pubmed/24829351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03823-13
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