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Ablation of Nectin4 Binding Compromises CD46 Usage by a Hybrid Vesicular Stomatitis Virus/Measles Virus

Measles virus (MV) immunosuppression is due to infection of SLAM-positive immune cells, whereas respiratory shedding and virus transmission are due to infection of nectin4-positive airway epithelial cells. The vaccine lineage MV strain Edmonston (MV-Edm) acquired an additional tropism for CD46 which...

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Detalhes bibliográficos
Main Authors: Liu, Yu-Ping, Russell, Samuel P., Ayala-Breton, Camilo, Russell, Stephen J., Peng, Kah-Whye
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911550/
https://ncbi.nlm.nih.gov/pubmed/24335299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02628-13
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