A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo

The mouse Period2 (mPer2) locus is an essential negative-feedback element of the mammalian circadian-clock mechanism. Recent work has shown that mPer2 circadian gene expression persists in both central and peripheral tissues. Here, we analyze the mouse mPer2 promoter and identify a circadian enhance...

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Detalhes bibliográficos
Main Authors: Yoo, Seung-Hee, Ko, Caroline H., Lowrey, Phillip L., Buhr, Ethan D., Song, Eun-joo, Chang, Suhwan, Yoo, Ook Joon, Yamazaki, Shin, Lee, Choogon, Takahashi, Joseph S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548324/
https://ncbi.nlm.nih.gov/pubmed/15699353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409763102
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