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Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism
Hepatic insulin resistance is a critical component in the development of type 2 diabetes mellitus. In many cases, insulin resistance in liver is associated with reduced expression of both major insulin receptor substrate (IRS) proteins, IRS-1 and IRS-2. To investigate the specific functions of IRS-1...
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| Udgivet i: | J Clin Invest |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548317/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15711641/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI23187 |
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