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Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism
Hepatic insulin resistance is a critical component in the development of type 2 diabetes mellitus. In many cases, insulin resistance in liver is associated with reduced expression of both major insulin receptor substrate (IRS) proteins, IRS-1 and IRS-2. To investigate the specific functions of IRS-1...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548317/ https://ncbi.nlm.nih.gov/pubmed/15711641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200523187 |
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