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Epstein-Barr virus-encoded LMP2A stimulates migration of nasopharyngeal carcinoma cells via the EGFR/Ca(2+)/calpain/ITGβ4 axis

Epstein-Barr virus (EBV)-encoded latent membrane protein 2A (LMP2A) promotes the motility of nasopharyngeal carcinoma (NPC) cells. Previously, we have shown that the localization of integrin β4 (ITGβ4) is regulated by LMP2A, with ITGβ4 concentrated at the cellular protrusions in LMP2A-expressing NPC...

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Bibliografiske detaljer
Udgivet i:Biol Open
Main Authors: Liang, Jiezhen, Zheng, Shixing, Xiao, Xue, Wei, Jiazhang, Zhang, Zhe, Ernberg, Ingemar, Matskova, Liudmila, Huang, Guangwu, Zhou, Xiaoying
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483025/
https://ncbi.nlm.nih.gov/pubmed/28512118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.024646
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