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Degradation of cofilin is regulated by Cbl, AIP4 and Syk resulting in increased migration of LMP2A positive nasopharyngeal carcinoma cells

Expression of cofilin is directly associated with metastatic activity in many tumors. Here, we studied the role of Latent Membrane Protein 2 A (LMP2A) of Epstein-Barr Virus (EBV) in the accumulation of cofilin observed in nasopharyngeal cancer (NPC) tumor cells. We used LMP2A transformed NPC cell li...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Gainullin, Murat R., Zhukov, Ilya Yu, Zhou, Xiaoying, Mo, Yingxi, Astakhova, Lidiia, Ernberg, Ingemar, Matskova, Liudmila
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567079/
https://ncbi.nlm.nih.gov/pubmed/28827787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09540-3
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