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Epstein-Barr virus-encoded LMP2A stimulates migration of nasopharyngeal carcinoma cells via the EGFR/Ca(2+)/calpain/ITGβ4 axis

Epstein-Barr virus (EBV)-encoded latent membrane protein 2A (LMP2A) promotes the motility of nasopharyngeal carcinoma (NPC) cells. Previously, we have shown that the localization of integrin β4 (ITGβ4) is regulated by LMP2A, with ITGβ4 concentrated at the cellular protrusions in LMP2A-expressing NPC...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Liang, Jiezhen, Zheng, Shixing, Xiao, Xue, Wei, Jiazhang, Zhang, Zhe, Ernberg, Ingemar, Matskova, Liudmila, Huang, Guangwu, Zhou, Xiaoying
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483025/
https://ncbi.nlm.nih.gov/pubmed/28512118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.024646
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