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C-Terminal Domain of the Epstein-Barr Virus LMP2A Membrane Protein Contains a Clustering Signal

The latency-regulated transmembrane protein LMP2A interferes with signaling from the B-cell antigen receptor by recruiting the tyrosine kinases Lyn and Syk and by targeting them for degradation by binding the cellular E3 ubiquitin ligase AIP4. It has been hypothesized that this constitutive activity...

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Detalhes bibliográficos
Main Authors: Matskova, Liudmila, Ernberg, Ingemar, Pawson, Tony, Winberg, Gösta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114674/
https://ncbi.nlm.nih.gov/pubmed/11602734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.10941-10949.2001
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