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C-Terminal Domain of the Epstein-Barr Virus LMP2A Membrane Protein Contains a Clustering Signal

The latency-regulated transmembrane protein LMP2A interferes with signaling from the B-cell antigen receptor by recruiting the tyrosine kinases Lyn and Syk and by targeting them for degradation by binding the cellular E3 ubiquitin ligase AIP4. It has been hypothesized that this constitutive activity...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Matskova, Liudmila, Ernberg, Ingemar, Pawson, Tony, Winberg, Gösta
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114674/
https://ncbi.nlm.nih.gov/pubmed/11602734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.10941-10949.2001
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