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PI3K Signaling in Cancer: Beyond AKT

The phosphoinositide 3-kinase (PI3K) signaling pathway is one of the most frequently altered pathways in human cancer and has a critical role in driving tumor initiation and progression. Although PI3K and its lipid product phosphatidylinositol-3,4,5-trisphosphate (PIP(3)) have been shown to activate...

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Dades bibliogràfiques
Publicat a:Curr Opin Cell Biol
Autors principals: Lien, Evan C., Dibble, Christian C., Toker, Alex
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482768/
https://ncbi.nlm.nih.gov/pubmed/28343126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2017.02.007
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