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PI3K Signaling in Cancer: Beyond AKT
The phosphoinositide 3-kinase (PI3K) signaling pathway is one of the most frequently altered pathways in human cancer and has a critical role in driving tumor initiation and progression. Although PI3K and its lipid product phosphatidylinositol-3,4,5-trisphosphate (PIP(3)) have been shown to activate...
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| Published in: | Curr Opin Cell Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5482768/ https://ncbi.nlm.nih.gov/pubmed/28343126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2017.02.007 |
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