Therapeutic inhibition of USP7-PTEN network in chronic lymphocytic leukemia: a strategy to overcome TP53 mutated/deleted clones

Chronic Lymphocytic Leukemia (CLL) is a lymphoproliferative disorder with either indolent or aggressive clinical course. Current treatment regiments have significantly improved the overall outcomes even if higher risk subgroups - those harboring TP53 mutations or deletions of the short arm of chromo...

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Pubblicato in:Oncotarget
Autori principali: Carrà, Giovanna, Panuzzo, Cristina, Torti, Davide, Parvis, Guido, Crivellaro, Sabrina, Familiari, Ubaldo, Volante, Marco, Morena, Deborah, Lingua, Marcello Francesco, Brancaccio, Mara, Guerrasio, Angelo, Pandolfi, Pier Paolo, Saglio, Giuseppe, Taulli, Riccardo, Morotti, Alessandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Priority Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482594/
https://ncbi.nlm.nih.gov/pubmed/28418900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16348
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