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The Role of PTEN in Myeloid Malignancies

PTEN deletion in the mouse and in the zebrafish highlights the essential role of this tumor suppressor in the development of myeloid malignancies, in particular acute myeloid leukemia and myeloproliferative disorders. In humans, extensive genetic sequences of myeloid malignancies did not reveal recu...

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Détails bibliographiques
Publié dans:Hematol Rep
Auteurs principaux: Morotti, Alessandro, Panuzzo, Cristina, Crivellaro, Sabrina, Carrà, Giovanna, Torti, Davide, Guerrasio, Angelo, Saglio, Giuseppe
Format: Artigo
Langue:Inglês
Publié: PAGEPress Publications, Pavia, Italy 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691678/
https://ncbi.nlm.nih.gov/pubmed/26734127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/hr.2015.6027
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