The Role of PTEN in Myeloid Malignancies

PTEN deletion in the mouse and in the zebrafish highlights the essential role of this tumor suppressor in the development of myeloid malignancies, in particular acute myeloid leukemia and myeloproliferative disorders. In humans, extensive genetic sequences of myeloid malignancies did not reveal recu...

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Bibliographic Details
Published in:Hematol Rep
Main Authors: Morotti, Alessandro, Panuzzo, Cristina, Crivellaro, Sabrina, Carrà, Giovanna, Torti, Davide, Guerrasio, Angelo, Saglio, Giuseppe
Format: Artigo
Language:Inglês
Published: PAGEPress Publications, Pavia, Italy 2015
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691678/
https://ncbi.nlm.nih.gov/pubmed/26734127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/hr.2015.6027
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