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Gene Therapy of Periodontal Disease by AAV-shRNA Silencing of Cathepsin K by inhibiting inflammation in periodontal lesion area

BACKGROUND AND OBJECTIVE: Periodontitis is a serious disease that affects the majority of adult population around the world. While great efforts have been devoted toward understanding the pathogenesis of periodontitis, there remains a pressing need for developing potent therapeutic strategies for ta...

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Bibliographische Detailangaben
Veröffentlicht in:J Periodontal Res
Hauptverfasser: Chen, Wei, Gao, Bo, Hao, Liang, Zhu, Guochun, Jules, Joel, Macdougall, Mary J., Han, Xiaozhe, Zhou, Xuedong, Li, Yi-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482270/
https://ncbi.nlm.nih.gov/pubmed/26754272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jre.12345
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