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Ac45 silencing mediated by AAV-sh-Ac45-RNAi prevents both bone loss and inflammation caused by periodontitis

AIM: Periodontitis induced by oral pathogens leads to severe periodontal tissue damage and osteoclast-mediated bone resorption caused by inflammation. Based on the importance of Ac45 in osteoclast formation and function, we performed this study to evaluate the therapeutic potential of periodontitis...

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Detalles Bibliográficos
Publicado en:J Clin Periodontol
Autores principales: Zhu, Zheng, Chen, Wei, Hao, Liang, Zhu, Guochun, Lu, Yun, Li, Sheng, Wang, Lin, Li, Yi-Ping
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620917/
https://ncbi.nlm.nih.gov/pubmed/25952706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcpe.12415
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