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RNAi-Mediated Silencing of Atp6i and Atp6i Haploinsufficiency Prevents Both Bone Loss and Inflammation in a Mouse Model of Periodontal Disease

Periodontal disease affects about 80% of adults in America, and is characterized by oral bacterial infection-induced gingival inflammation, oral bone resorption, and tooth loss. Periodontitis is also associated with other diseases such as rheumatoid arthritis, diabetes, and heart disease. Although m...

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Detalhes bibliográficos
Main Authors: Jiang, Hongbing, Chen, Wei, Zhu, Guochun, Zhang, Lijie, Tucker, Byron, Hao, Liang, Feng, Shengmei, Ci, Hongliang, Ma, Junqing, Wang, Lin, Stashenko, Philip, Li, Yi-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618217/
https://ncbi.nlm.nih.gov/pubmed/23577057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058599
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