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Engineering Periodic shRNA for Enhanced Silencing Efficacy
RNA interference (RNAi) provides a versatile therapeutic approach via silencing of specific genes, particularly undruggable targets in cancer and other diseases. However, challenges in the delivery of small interfering RNA (siRNA) have hampered clinical translation. Polymeric or periodic short hairp...
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| Yayımlandı: | Mol Ther |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4923333/ https://ncbi.nlm.nih.gov/pubmed/27053374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.69 |
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