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Enhanced salt sensitivity following shRNA silencing of neuronal TRPV1 in rat spinal cord

AIM: To investigate the effects of selective knockdown of TRPV1 channels in the lower thoracic and upper lumbar segments of spinal cord, dorsal root ganglia (DRG) and mesenteric arteries on rat blood pressure responses to high salt intake. METHODS: TRPV1 short-hairpin RNA (shRNA) was delivered using...

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Библиографические подробности
Главные авторы: Yu, Shuang-quan, Wang, Donna H
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009958/
https://ncbi.nlm.nih.gov/pubmed/21642952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.43
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