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Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts
During bone remodelling, osteoclasts induce chemotaxis of osteoblasts and yet maintain spatial segregation. We show that osteoclasts express the repulsive guidance factor Semaphorin 4D and induce contact inhibition of locomotion (CIL) in osteoblasts through its receptor Plexin-B1. To examine causali...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5482063/ https://ncbi.nlm.nih.gov/pubmed/28635959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15831 |
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