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Pharmacokinetic and pharmacodynamic modeling of cyadox against Clostridium perfringens in swine

The purpose of this study was to evaluate the activity of cyadox against Clostridium perfringens in swine and optimize the dosage regimen using ex vivo pharmacokinetic-pharmacodynamic (PK-PD) modeling. After oral administration, the ileum fluid of pigs containing the free cyadox was collected by imp...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Yan, Lei, Xie, Shuyu, Chen, Dongmei, Pan, Yuanhu, Tao, Yanfei, Qu, Wei, Liu, ZhenLi, Yuan, Zonghui, Huang, Lingli
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481453/
https://ncbi.nlm.nih.gov/pubmed/28642571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03970-9
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