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Pharmacokinetic and pharmacodynamic modeling of cyadox against Clostridium perfringens in swine

The purpose of this study was to evaluate the activity of cyadox against Clostridium perfringens in swine and optimize the dosage regimen using ex vivo pharmacokinetic-pharmacodynamic (PK-PD) modeling. After oral administration, the ileum fluid of pigs containing the free cyadox was collected by imp...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Yan, Lei, Xie, Shuyu, Chen, Dongmei, Pan, Yuanhu, Tao, Yanfei, Qu, Wei, Liu, ZhenLi, Yuan, Zonghui, Huang, Lingli
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481453/
https://ncbi.nlm.nih.gov/pubmed/28642571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03970-9
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