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Pharmacokinetic and pharmacodynamic modeling of cyadox against Clostridium perfringens in swine

The purpose of this study was to evaluate the activity of cyadox against Clostridium perfringens in swine and optimize the dosage regimen using ex vivo pharmacokinetic-pharmacodynamic (PK-PD) modeling. After oral administration, the ileum fluid of pigs containing the free cyadox was collected by imp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yan, Lei, Xie, Shuyu, Chen, Dongmei, Pan, Yuanhu, Tao, Yanfei, Qu, Wei, Liu, ZhenLi, Yuan, Zonghui, Huang, Lingli
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481453/
https://ncbi.nlm.nih.gov/pubmed/28642571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03970-9
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