Pharmacokinetics and Metabolism of Cyadox and Its Main Metabolites in Beagle Dogs Following Oral, Intramuscular, and Intravenous Administration

Cyadox (Cyx) is an antibacterial drug of the quinoxaline group that exerts markedly lower toxicity in animals, compared to its congeners. Here, the pharmacokinetics and metabolism of Cyx after oral (PO), intramuscular (IM), and intravenous (IV) routes of administration were studied to establish safe...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Sattar, Adeel, Xie, Shuyu, Huang, Lingli, Iqbal, Zahid, Qu, Wei, Shabbir, Muhammad A., Pan, Yuanhu, Hussain, Hafiz I., Chen, Dongmei, Tao, Yanfei, Liu, Zhenli, Iqbal, Mujahid, Yuan, Zonghui
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971586/
https://ncbi.nlm.nih.gov/pubmed/27536243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00236
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