Pharmacokinetics and Metabolism of Cyadox and Its Main Metabolites in Beagle Dogs Following Oral, Intramuscular, and Intravenous Administration

Cyadox (Cyx) is an antibacterial drug of the quinoxaline group that exerts markedly lower toxicity in animals, compared to its congeners. Here, the pharmacokinetics and metabolism of Cyx after oral (PO), intramuscular (IM), and intravenous (IV) routes of administration were studied to establish safe...

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Vydáno v:Front Pharmacol
Hlavní autoři: Sattar, Adeel, Xie, Shuyu, Huang, Lingli, Iqbal, Zahid, Qu, Wei, Shabbir, Muhammad A., Pan, Yuanhu, Hussain, Hafiz I., Chen, Dongmei, Tao, Yanfei, Liu, Zhenli, Iqbal, Mujahid, Yuan, Zonghui
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971586/
https://ncbi.nlm.nih.gov/pubmed/27536243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00236
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