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On the mechanistic nature of epistasis in a canonical cis-regulatory element

Understanding the relation between genotype and phenotype remains a major challenge. The difficulty of predicting individual mutation effects, and particularly the interactions between them, has prevented the development of a comprehensive theory that links genotypic changes to their phenotypic effe...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Lagator, Mato, Paixão, Tiago, Barton, Nicholas H, Bollback, Jonathan P, Guet, Călin C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481185/
https://ncbi.nlm.nih.gov/pubmed/28518057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25192
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