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Regulatory network structure determines patterns of intermolecular epistasis

Most phenotypes are determined by molecular systems composed of specifically interacting molecules. However, unlike for individual components, little is known about the distributions of mutational effects of molecular systems as a whole. We ask how the distribution of mutational effects of a transcr...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Lagator, Mato, Sarikas, Srdjan, Acar, Hande, Bollback, Jonathan P, Guet, Călin C
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699867/
https://ncbi.nlm.nih.gov/pubmed/29130883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28921
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