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Redundancy and the Evolution of Cis-Regulatory Element Multiplicity

The promoter regions of many genes contain multiple binding sites for the same transcription factor (TF). One possibility is that this multiplicity evolved through transitional forms showing redundant cis-regulation. To evaluate this hypothesis, we must disentangle the relative contributions of diff...

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Detalhes bibliográficos
Main Authors: Paixão, Tiago, Azevedo, Ricardo B. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900288/
https://ncbi.nlm.nih.gov/pubmed/20628617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000848
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