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Redundancy and the Evolution of Cis-Regulatory Element Multiplicity

The promoter regions of many genes contain multiple binding sites for the same transcription factor (TF). One possibility is that this multiplicity evolved through transitional forms showing redundant cis-regulation. To evaluate this hypothesis, we must disentangle the relative contributions of diff...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Paixão, Tiago, Azevedo, Ricardo B. R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900288/
https://ncbi.nlm.nih.gov/pubmed/20628617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000848
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