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Redundancy and the Evolution of Cis-Regulatory Element Multiplicity
The promoter regions of many genes contain multiple binding sites for the same transcription factor (TF). One possibility is that this multiplicity evolved through transitional forms showing redundant cis-regulation. To evaluate this hypothesis, we must disentangle the relative contributions of diff...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900288/ https://ncbi.nlm.nih.gov/pubmed/20628617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000848 |
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