Chromatin Architecture near a Potential 3′ End of the Igh Locus Involves Modular Regulation of Histone Modifications during B-Cell Development and In Vivo Occupancy at CTCF Sites

The murine Igh locus has a 3′ regulatory region (3′ RR) containing four enhancers (hs3A, hs1,2, hs3B, and hs4) at DNase I-hypersensitive sites. The 3′ RR exerts long-range effects on class switch recombination (CSR) to several isotypes through its control of germ line transcription. By measuring lev...

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Detalhes bibliográficos
Main Authors: Garrett, Francine E., Emelyanov, Alexander V., Sepulveda, Manuel A., Flanagan, Patrick, Volpi, Sabrina, Li, Fubin, Loukinov, Dmitry, Eckhardt, Laurel A., Lobanenkov, Victor V., Birshtein, Barbara K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548023/
https://ncbi.nlm.nih.gov/pubmed/15684400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.4.1511-1525.2005
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