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Polypyrimidine Tract-Binding Protein Enhances the Internal Ribosomal Entry Site-Dependent Translation of p27(Kip1) mRNA and Modulates Transition from G(1) to S Phase
The p27(Kip1) protein plays a critical role in the regulation of cell proliferation through the inhibition of cyclin-dependent kinase activity. Translation of p27(Kip1) is directed by an internal ribosomal entry site (IRES) in the 5′ nontranslated region of p27(Kip1) mRNA. Here, we report that polyp...
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| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548013/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15684381/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.4.1283-1297.2005 |
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