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Polypyrimidine Tract-Binding Protein Enhances the Internal Ribosomal Entry Site-Dependent Translation of p27(Kip1) mRNA and Modulates Transition from G(1) to S Phase
The p27(Kip1) protein plays a critical role in the regulation of cell proliferation through the inhibition of cyclin-dependent kinase activity. Translation of p27(Kip1) is directed by an internal ribosomal entry site (IRES) in the 5′ nontranslated region of p27(Kip1) mRNA. Here, we report that polyp...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548013/ https://ncbi.nlm.nih.gov/pubmed/15684381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.4.1283-1297.2005 |
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