A Cellular RNA-Binding Protein Enhances Internal Ribosomal Entry Site-Dependent Translation through an Interaction Downstream of the Hepatitis C Virus Polyprotein Initiation Codon

Translational initiation of hepatitis C virus (HCV) mRNA occurs by internal entry of ribosomes into an internal ribosomal entry site (IRES) at the 5′ nontranslated region. A region encoding the N-terminal part of the HCV polyprotein has been shown to augment the translation of HCV mRNA. Here we show...

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Bibliographic Details
Main Authors: Kim, Jong Heon, Paek, Ki Young, Ha, Sang Hoon, Cho, Sungchan, Choi, Kobong, Kim, Chon Saeng, Ryu, Sung Ho, Jang, Sung Key
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC515056/
https://ncbi.nlm.nih.gov/pubmed/15340051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.7878-7890.2004
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