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Ritonavir and ixazomib kill bladder cancer cells by causing ubiquitinated protein accumulation

There is no curative treatment for advanced bladder cancer. Causing ubiquitinated protein accumulation and endoplasmic reticulum stress is a novel approach to cancer treatment. The HIV protease inhibitor ritonavir has been reported to suppress heat shock protein 90 and increase the amount of unfolde...

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Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Sato, Akinori, Asano, Takako, Okubo, Kazuki, Isono, Makoto, Asano, Tomohiko
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480085/
https://ncbi.nlm.nih.gov/pubmed/28342223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13242
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