Bortezomib and belinostat inhibit renal cancer growth synergistically by causing ubiquitinated protein accumulation and endoplasmic reticulum stress

There is no curative treatment for advanced renal cancer, and a novel treatment approach is urgently required. Inducing ubiquitinated protein accumulation and endoplasmic reticulum (ER) stress has recently emerged as a new approach in the treatment of malignancies. In the present study, we hypothesi...

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Udgivet i:Biomed Rep
Main Authors: ASANO, TAKAKO, SATO, AKINORI, ISONO, MAKOTO, OKUBO, KAZUKI, ITO, KEIICHI, ASANO, TOMOHIKO
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660644/
https://ncbi.nlm.nih.gov/pubmed/26623018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2015.523
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