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Ritonavir Interacts With Belinostat to Cause Endoplasmic Reticulum Stress and Histone Acetylation in Renal Cancer Cells

The histone deacetylase (HDAC) inhibitor belinostat increases the amount of unfolded proteins in cells by promoting the acetylation of heat shock protein 90 (HSP90), thereby disrupting its chaperone function. The human immunodeficiency virus protease inhibitor ritonavir, on the other hand, not only...

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Bibliografske podrobnosti
izdano v:Oncol Res
Main Authors: Isono, Makoto, Sato, Akinori, Okubo, Kazuki, Asano, Takako, Asano, Tomohiko
Format: Artigo
Jezik:Inglês
Izdano: Cognizant Communication Corporation 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838685/
https://ncbi.nlm.nih.gov/pubmed/27712589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504016X14666990347635
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